Ms. Ann Kurian | Biomaterials | Best Researcher Award

Ann Anu Kurian is a biomedical researcher with over seven years of experience specializing in cellular biology and RNA-based gene delivery. She holds an MS in Biomedical Science from Morehouse School of Medicine and a BTech in Biotechnology from Lovely Professional University. Currently an Associate Researcher II and Lab Manager at the Icahn School of Medicine at Mount Sinai, her work focuses on cardiac and skeletal muscle regeneration using modified mRNA technologies. She has contributed to multiple peer-reviewed publications and has been recognized with several academic honors, including a Presidential Scholarship and research presentation awards.

Ms.Ann Kurian , Icahn school of medicine, United States.

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πŸŽ“ Education

Ann Anu Kurian holds a Master of Science in Biomedical Science from Morehouse School of Medicine in Atlanta, Georgia, completed between August 2015 and May 2017. She also earned a Bachelor of Technology in Biotechnology from Lovely Professional University in India, where she studied from August 2009 to May 2013.

🌟 Experience

With over seven years of research experience, Ann currently serves as an Associate Researcher II and Research Lab Manager at the Icahn School of Medicine at Mount Sinai in New York. Since November 2023, she has been working in the Gregorio Laboratory, conducting research focused on understanding the components and molecular mechanisms that regulate actin architecture in cardiac and skeletal muscle during both normal development and disease. Prior to this, she held a similar role in the Zangi Laboratory from August 2017 to November 2023, where she led projects utilizing modified mRNA to improve cardiac outcomes post-injury and managed various aspects of laboratory operations. Her professional journey began in India at VWR International from January 2014 to August 2015, where she supported chemical projects, maintained product data in SAP, and enhanced product descriptions.

πŸ… Awards and Honors

Ann has been recognized for her academic and research achievements, receiving a Presidential Scholarship from Morehouse School of Medicine in 2017. The same year, she earned a travel award to attend the Georgia Academy of Science annual meeting. She also presented her research at several prestigious conferences, including the Ninth AACR Conference on The Science of Cancer Health Disparities, the Curtis L. Parker Student Research Symposium, and the Georgia Academy of Science annual meeting.

πŸ“–Skill

Ann is skilled in a wide range of technical and laboratory techniques. Her expertise includes molecular biology methods such as PCR, gel electrophoresis, cloning, RNA and DNA extraction, modified mRNA production, and LNP characterization. She is proficient in cell culture techniques, cardiomyocyte isolation, tissue sectioning, histological staining, and confocal microscopy. Her experience also includes data analysis, IVIS imaging, and statistical evaluation. She has strong capabilities in animal handling and laboratory management, including procurement, equipment maintenance, and regulatory compliance.

πŸ”¬ Research Focus

Ann’s research centers on cellular biology and RNA-based gene delivery systems, particularly in the context of cardiac and skeletal muscle biology. Her work has explored the use of modified mRNA technologies to induce gene expression for therapeutic regeneration following cardiac injury. Her contributions to the field are reflected in numerous peer-reviewed publications, addressing areas such as cardiomyocyte proliferation, ischemic injury, cardiac regeneration, and mRNA optimization.

πŸ“˜ Publications

Pkm2 regulates cardiomyocyte cell cycle and promotes cardiac regeneration
Authors: A Magadum, N Singh, AA Kurian, I Munir, T Mehmood, K Brown, …
Year: 2020
Journal: Circulation (Volume 141, Issue 15, Pages 1249–1265)

Altering sphingolipid metabolism attenuates cell death and inflammatory response after myocardial infarction
Authors: Y Hadas, AS Vincek, E Youssef, MM Ε»ak, E Chepurko, N Sultana, …
Year: 2020
Journal: Circulation (Volume 141, Issue 11, Pages 916–930)

Ablation of a single N-glycosylation site in human FSTL 1 induces cardiomyocyte proliferation and cardiac regeneration
Authors: A Magadum, N Singh, AA Kurian, MTK Sharkar, E Chepurko, L Zangi
Year: 2018
Journal: Molecular Therapy – Nucleic Acids (Volume 13, Pages 133–143)

Optimization of 5β€² untranslated region of modified mRNA for use in cardiac or hepatic ischemic injury
Authors: N Sultana, Y Hadas, MTK Sharkar, K Kaur, A Magadum, AA Kurian, …
Year: 2020
Journal: Molecular Therapy Methods & Clinical Development (Volume 17, Pages 622–633)

Direct reprogramming induces vascular regeneration post muscle ischemic injury
Authors: K Kaur, Y Hadas, AA Kurian, MM Ε»ak, J Yoo, A Mahmood, H Girard, …
Year: (Year not provided)
Journal: Molecular Therapy (Volume 29, Issue 10, Pages 3042–3058)

Ann Kurian | Biomaterials | Best Researcher Award