Prof Yuri Lyubchenko | Biomaterials | Best Researcher Award
Prof. Yuri Lyubchenko 🎓🧬 is a globally renowned biophysicist and nanotechnologist whose groundbreaking research spans neurodegenerative diseases 🧠, cancer biology 🧫, HIV research 🧪, and nanoimaging 🔬. With advanced degrees in Chemical Kinetics, Molecular Biophysics, and Molecular Biology, he pioneered the on-surface aggregation mechanism for amyloids and developed high-resolution AFM techniques to probe biomolecular structures at the nanoscale. 🧿 A Distinguished Scientist at UNMC 🌟, Prof. Lyubchenko has over 200 publications and has served on major NIH, NSF, and DOE panels. His innovative work continues to reshape our understanding of human disease and molecular biology on a global scale. 🌍✨
Prof Yuri Lyubchenko, University of Nebraska Medical Center, United States
Profile
🎓 Education
Prof. Yuri Lyubchenko’s academic journey began at the prestigious Moscow Institute of Physics and Technology 🇷🇺, where he earned an M.S. in Chemical Kinetics ⚗️ in 1968. He then advanced to a Ph.D. in Molecular Biophysics 🧬 by 1971, and later crowned his academic accomplishments with a D.Sc. in Molecular Biology 🧫 in 1989 at the Institute of Molecular Genetics, Moscow. This exceptional educational foundation laid the groundwork for a pioneering career in biomedical research, empowering him to tackle complex biological questions with atomic-level precision and innovation. 🌍📚✨
🏅 Honors
In 2008, Prof. Yuri Lyubchenko was honored as a Distinguished Scientist 🏆 at the University of Nebraska Medical Center, acknowledging his remarkable contributions to biomedical research. His service to the scientific community spans across elite institutions—he has served on NIH study sections, NCI intramural research panels, as well as NSF and DOE review boards 🧪📊. As an associate and academic editor ✍️ for over a dozen high-impact journals, he continues to shape scientific discourse worldwide. His leadership, credibility, and dedication make him a pillar in the global research ecosystem 🌐🧠.
🧬 Research Leadership
Prof. Yuri Lyubchenko has held a series of impactful roles across top-tier institutions worldwide. Since 2004, he has served as Professor at the University of Nebraska Medical Center 🏫. His earlier appointments include key research positions at Arizona State University 🔬 and the University of Nevada Reno 🌄. Prior to his U.S. appointments, he led pioneering molecular biology work at the USSR Academy of Sciences 🇷🇺. From junior scientist to senior leadership roles, his journey through academia and global research centers reflects an extraordinary legacy of commitment, discovery, and innovation in the life sciences 🌟🧪.
🔬 Research Focus
Prof. Yuri Lyubchenko’s research is at the forefront of structural biology, focusing on the mechanistic regulation of DNA-protein interactions, chromatin dynamics, and amyloid aggregation—key to understanding neurodegenerative diseases 🧠. He has revolutionized the application of atomic force microscopy (AFM) 🧫 for nanoscale visualization of DNA, RNA, and protein complexes in various environments 🌊. His work on beta-amyloid aggregation and PARP-1 regulation has been widely cited, reflecting a lasting impact on neuroscience and molecular genetics 📈. Prof. Lyubchenko’s research bridges nanotechnology with biology, offering transformative tools and perspectives for biomedical science ⚙️🧪.
📘 Publications
Regulation of poly (ADP-ribose) polymerase-1 by DNA structure-specific binding
👨🔬 I. Lonskaya, V.N. Potaman, L.S. Shlyakhtenko, E.A. Oussatcheva, Y.L. Lyubchenko, et al.
🧪 Journal of Biological Chemistry, 280 (17), 17076–17083 (2005)
📊 Citations: 265
🧬🧠 DNA Repair | Protein Interaction | Structural Biology
Atomic force microscopy imaging of double-stranded DNA and RNA
👨🔬 Y.L. Lyubchenko, A.A. Gall, L.S. Shlyakhtenko, R.E. Harrington, B.L. Jacobs, et al.
🧪 Journal of Biomolecular Structure and Dynamics, 10 (3), 589–606 (1992)
📊 Citations: 252
🔬🧬 Visualization | AFM | Molecular Structure
Atomic force microscopy of DNA and bacteriophage in air, water and propanol: the role of adhesion forces
👨🔬 Y.L. Lyubchenko, P.I. Oden, D. Lampner, S.M. Lindsay, K.A. Dunker
🧪 Nucleic Acids Research, 21 (5), 1117–1123 (1993)
📊 Citations: 232
🧲🦠 DNA Imaging | Nanotechnology | Surface Chemistry
Residues 17–20 and 30–35 of beta‐amyloid play critical roles in aggregation
👨🔬 R. Liu, C. McAllister, Y. Lyubchenko, M.R. Sierks
🧪 Journal of Neuroscience Research, 75 (2), 162–171 (2004)
📊 Citations: 229
🧠🧩 Alzheimer’s Disease | Protein Aggregation | Amyloids
🔍 5. Comparative studies of bacteria with an atomic force microscopy operating in different modes
👨🔬 A.V. Bolshakova, O.I. Kiselyova, A.S. Filonov, O.Y. Frolova, Y.L. Lyubchenko, et al.
🧪 Ultramicroscopy, 86 (1–2), 121–128 (2001)
📊 Citations: 226
🦠🔬 Bacteria | AFM Techniques | Surface Analysis
AFM for analysis of structure and dynamics of DNA and protein–DNA complexes
👨🔬 Y.L. Lyubchenko, L.S. Shlyakhtenko
🧪 Methods, 47 (3), 206–213 (2009)
📊 Citations: 222
🔬🧬 DNA-Protein Interactions | Method Development | AFM